Moszczyński P, Rutowski J, Słowiński S, Jakus-Stoga D
Z Wojewódzkiej Pracowni Immunologicznej w Brzesku.
Przegl Lek. 1996;53(3):143-6.
The count of lymphocytes, lymphocytes T (CD 3+), lymphocytes T-helper (CD 4+), T-suppressor (CD 8+) and NK-cells (CD 16+) as well as immunoglobulins A, D, G, M, complements C3c and C4, alpha 1-acid glycoprotein, haptoglobin, ceruloplasmin and transferrin were detected in males exposed to mercury vapours and in males of the control groups. The shift time weight average (TWA) of mercury in ambient air was 0,028 mg x m-3. Mean mercury concentration was from 0 to 240 micrograms x 1(-1) in urine of the study group and from 0-30 micrograms x 1(-1) in blood. Stimulation of lymphocytes system, manifested by an increase number of lymphocytes T, T-helper and T-suppressor in the peripheral blood was observed. Higher increase of T-suppressor cells than T-helper populations was the case of decreased value of the T-helper/T-suppressor ratio by 20.5% (p < 0.05) in workers exposed below 10 or by 21% (p < 0.05) in workers exposed over 10 years. Decrease of immunoglobulin A, G and M concentration in serum of workers exposed to mercury vapours over 20 years was also observed. The concentrations of IgG, C3c, C4 and determined acute phase proteins in serum of exposed subjects did not differ from that in the non-exposed subjects.
对接触汞蒸气的男性和对照组男性的淋巴细胞、T淋巴细胞（CD 3+）、辅助性T淋巴细胞（CD 4+）、抑制性T淋巴细胞（CD 8+）和自然杀伤细胞（CD 16+）计数，以及免疫球蛋白A、D、G、M、补体C3c和C4、α1-酸性糖蛋白、触珠蛋白、铜蓝蛋白和转铁蛋白进行了检测。环境空气中汞的时间加权平均浓度（TWA）为0.028毫克×立方米-3。研究组尿液中汞的平均浓度为0至240微克×升-1，血液中为0至30微克×升-1。观察到淋巴细胞系统受到刺激，表现为外周血中T淋巴细胞、辅助性T淋巴细胞和抑制性T淋巴细胞数量增加。在接触汞低于10年的工人中，抑制性T细胞的增加高于辅助性T细胞群体，辅助性T细胞/抑制性T细胞比值降低了20.5%（p<0.05）；在接触汞超过10年的工人中，该比值降低了21%（p<0.05）。还观察到接触汞蒸气超过20年的工人血清中免疫球蛋白A、G和M浓度降低。接触组血清中IgG、C3c、C4以及测定的急性期蛋白浓度与未接触组无差异。
