Gorelova L A, Zemskova Z S, Panasek I A, Nekrasov A V, Puchkova N G, Moroz A M, Romanova R Iu
Probl Tuberk. 1996(3):46-7.
CBA mice served as experimental tuberculosis model to study protective, immunomodulating and toxico-allergic properties of two drugs including cytoplasma and cell walls of BCG mycobacteria as well as of synthetic adjuvant polyoxidonium. Doses and schemes are presented developed for experimental tuberculosis treatment with cytoplasm and not causing toxico-allergic reactions in mice. The specific immunomodulator of cytoplasm, polyoxidonium, proved effective therapeutic modality in experimental mouse tuberculosis.
CBA 小鼠作为实验性结核病模型，用于研究两种药物的保护、免疫调节和毒理过敏特性，这两种药物包括卡介苗分枝杆菌的细胞质和细胞壁以及合成佐剂聚氧化乙烯。文中给出了针对用细胞质治疗实验性结核病且不会在小鼠中引起毒理过敏反应所制定的剂量和方案。细胞质的特异性免疫调节剂聚氧化乙烯，在实验性小鼠结核病中被证明是一种有效的治疗方式。
