Kołaczkowska M, Młynarczyk W, Rzymkowska M
Kliniki Pneumonologii Instytutu Chorób Wewnetrzych AM w Poznaniu.
Pneumonol Alergol Pol. 1996;64(3-4):196-203.
This work evaluates frequency of steroid induced osteoporosis according to kind of steroid drugs (systemic, inhaled), dose and duration of treatment. In group of 80 young patients with asthma and chronic bronchitis the following examinations have been used: biochemical markers of bone turnover, X-ray of thoracic lumbar part of vertebral column and bone density in quantitative computed tomography of vertebrae L2-L4. Osteoporosis appeared in patients chronically treated with systemic steroids (prednisone) and in patients treated with inhaled steroids in typical dose as well. Usefulness of biochemical markers of bone turnover in connection with quantitative computed tomography in diagnostic of steroid induced osteoporosis has been confirmed.
这项研究根据类固醇药物的种类（全身性、吸入性）、剂量和治疗持续时间评估类固醇诱导骨质疏松症的发生率。在80名患有哮喘和慢性支气管炎的年轻患者组中，采用了以下检查：骨转换的生化标志物、胸腰椎X线检查以及L2-L4椎体定量计算机断层扫描中的骨密度检查。长期接受全身性类固醇（泼尼松）治疗的患者以及接受典型剂量吸入性类固醇治疗的患者均出现了骨质疏松症。骨转换生化标志物与定量计算机断层扫描相结合在诊断类固醇诱导骨质疏松症方面的有效性得到了证实。
