Campbell W H, Johnson R E, Senft R A, Azevedo D J
Med Care. 1977 Jul;15(7):599-608. doi: 10.1097/00005650-197707000-00007.
Adverse drug reactions represent an area of concern in the delivery of medical care. Current data available indicating the nature and extent of the problem of adverse drug reactions are recognized as inadequate for policy making. This study contributes new information about the adverse effects of drugs treated in an outpatient population. The findings showed that the adverse effects of oral contraceptives accounted for a large share of medical care contacts, procedures rendered, and estimated dollars expended. The incidence and prevalence rates indicated relatively few persons among the population were treated for adverse effects of drugs. Annual costs to the medical care system of treating adverse drug effects were estimated to be $.83 per person. Additional information is needed about adverse drug reactions if strategies and approaches to deal with adverse effects of drugs are to be efficient and effective.
药物不良反应是医疗护理中的一个关注点。目前可得的数据表明，关于药物不良反应问题的性质和程度，被认为不足以用于决策。本研究提供了有关门诊患者所治疗药物不良反应的新信息。研究结果显示，口服避孕药的不良反应在医疗护理接触、实施的程序以及估计的费用支出中占了很大比例。发病率和患病率表明，人群中因药物不良反应接受治疗的人数相对较少。医疗系统治疗药物不良反应的年度成本估计为每人0.83美元。如果要使应对药物不良反应的策略和方法高效且有效，就需要更多关于药物不良反应的信息。
