Iacconi P, Aldi R, Bucceri R, Bendinelli C, Barsotti F, Miccoli P
Università degli Studi di Pisa, Dipartimento di Chirurgia.
G Chir. 1996 May;17(5):231-4.
Total colectomy with IRA in ulcerative colitis, Crohn's disease, familial polyposis and multicentric colonic cancer is still debated. In this paper the Authors present their experience with a retrospective review of 57 patients, treated in the Surgical Department of Pisa's University from 1978 to 1990. Through the results obtained, it is concluded that total colectomy with IRA is a valid procedure in the treatment of multiple polyposis, but must be associated with a long and careful follow up using fulguration for local recurrence. The usefulness of this treatment in multicentric colonic cancer is confirmed. However, the use of IRA in ulcerative colitis is debatable. This series shows the failure of colectomy with IRA in patients with Crohn's disease, due to the high incidence of local recurrences requiring reoperation.
对于溃疡性结肠炎、克罗恩病、家族性息肉病和多中心结肠癌患者,行全结肠切除术加回肠肛管吻合术(IRA)仍存在争议。在本文中,作者回顾性分析了1978年至1990年在比萨大学外科接受治疗的57例患者的经验。通过所获得的结果得出结论,全结肠切除术加IRA是治疗多发性息肉病的有效方法,但必须长期密切随访,并使用电灼术处理局部复发。该治疗方法在多中心结肠癌中的有效性得到了证实。然而,IRA在溃疡性结肠炎中的应用存在争议。本系列研究表明,由于局部复发率高且需要再次手术,克罗恩病患者行全结肠切除术加IRA治疗效果不佳。