Schroeder H W, Gaab M R, Niendorf W R
Department of Neurosurgery, Ernst-Moritz-Arndt University, Greifswald, Germany.
J Neurosurg. 1996 Aug;85(2):293-8. doi: 10.3171/jns.1996.85.2.0293.
A prospective study of seven consecutive patients with congenital arachnoid cysts treated endoscopically is reported. The ages of the patients at the time of diagnosis ranged from 6 to 47 years with three patients under 15 years. Two cysts were located in the posterior cranial fossa, four in the middle cranial fossa, and one in the suprasellar-prepontine area. The patients' symptoms included headache, seizures, vomiting, nausea, dizziness, balance problems, and precocious puberty. The authors performed cystocisternostomies and ventriculocystostomies via burr holes with the aid of a universal neuroendoscopic system. Minor bleeding was easily controlled by rinsing. In one case, the endoscopic procedure had to be abandoned because of significant bleeding, which obscured a clear operative view, and an open microsurgical cyst fenestration was performed. The follow-up review periods in this group of patients ranged from 15 to 30 months. There was no mortality or morbidity. Symptoms were relieved in five patients and improved in one. Precocious puberty in one case continued. In six cases, follow-up magnetic resonance images or computerized tomography scans revealed a decrease in the size of the cysts. Although the follow-up period is too short to make statements on long-term outcome, the authors recommend the minimally invasive endoscopic approach for treatment of arachnoid cysts as the first therapy of choice. Should the endoscopic procedure fail, established treatment options such as microsurgical fenestration or cystoperitoneal shunting can subsequently be performed without causing additional risk to the patient.
本文报道了对7例连续接受内镜治疗的先天性蛛网膜囊肿患者的前瞻性研究。诊断时患者年龄在6至47岁之间,其中3例年龄小于15岁。2个囊肿位于后颅窝,4个位于中颅窝,1个位于鞍上-脑桥前区。患者症状包括头痛、癫痫发作、呕吐、恶心、头晕、平衡问题和性早熟。作者借助通用神经内镜系统通过钻孔进行囊肿脑池造瘘术和脑室囊肿造瘘术。轻微出血通过冲洗很容易控制。1例因出血严重导致手术视野不清而不得不放弃内镜手术,改行开放性显微手术囊肿开窗术。该组患者的随访时间为15至30个月。无死亡或并发症发生。5例患者症状缓解,1例改善。1例性早熟持续存在。6例患者的随访磁共振成像或计算机断层扫描显示囊肿大小减小。尽管随访期太短无法对长期结果作出说明,但作者推荐将微创内镜治疗蛛网膜囊肿作为首选的初始治疗方法。如果内镜手术失败,随后可进行既定的治疗选择,如显微手术开窗或囊肿-腹腔分流术,而不会给患者带来额外风险。