Rao K V
Lloydia. 1977 Mar-Apr;40(2):169-72.
Hippomanin A is a pale yellow crystalline toxic principle isolated from the water-soluble portion of the ethanolic extract of Hippomane mancinella. Acid hydrolysis gave glucose, gallic acid and ellagic acid, thus showing that it belonged to the class of "crystalline tannins" and was isomeric with corilagin. The presence of free anomeric hydroxyl was shown by methylation and by reduction with sodium borohydride. Mass spectral and chemical evidence showed that the structure was 2-galloyl-4,6-hexahydroxydiphenoyl-D-glucose.
马疯大戟木素A是从马疯大戟乙醇提取物的水溶性部分分离得到的一种淡黄色结晶性有毒成分。酸水解得到葡萄糖、没食子酸和鞣花酸，表明它属于“结晶单宁”类，且与柯里拉京是同分异构体。通过甲基化和硼氢化钠还原证明存在游离异头羟基。质谱和化学证据表明其结构为2-没食子酰基-4,6-六羟基二苯甲酰基-D-葡萄糖。
