Horváth A, Fedorcsák I, Kontra G, Bajcsay A, Osztie E
Haynal Imre Egészségtudományi Egyetem, Sugárterápiás Tanszék, Budapest.
Orv Hetil. 1996 Jul 21;137(29):1579-82.
Authors render an account of their four years clinical experiences with linac-based stereotaxic radiosurgery. The first Hungarian stereotaxic radiosurgery team have treated 166 patients between 01. 07. 1991 and 01. 11. 1995: 86 suffered from brain metastases, 13 of them had primary brain tumors 35, benign brain lesions and 32 arteriovenous malformations. The local control rate was found similar to presented in the literature (83, 77, 57 and 82%). During 9 months of median follow up 44% of brain metastatic cases are alive and only 12% died because of cerebral propagation. The primary brain tumors were mostly recurrences (77%) after surgery and/or conventional radiotherapy, 31% died in 11 months of median follow up. Treating benignomas and arteriovenous malformations there was no need for craniotomy at 68 patients. No fatal complications were observed, the rare side-effects seemed to be manageable. The method is an effective possibility for the non-invasive treatment of the above mentioned brain lesions.
作者介绍了他们使用直线加速器立体定向放射外科的四年临床经验。匈牙利首个立体定向放射外科团队在1991年7月1日至1995年11月1日期间治疗了166例患者:86例患有脑转移瘤,其中13例患有原发性脑肿瘤,35例为良性脑病变,32例为动静脉畸形。发现局部控制率与文献报道相似(分别为83%、77%、57%和82%)。在中位随访9个月期间,44%的脑转移病例存活,仅12%因脑转移死亡。原发性脑肿瘤大多为手术后和/或传统放疗后的复发(77%),31%在中位随访11个月时死亡。在治疗68例良性肿瘤和动静脉畸形患者时无需开颅手术。未观察到致命并发症,罕见的副作用似乎可以控制。该方法是上述脑病变无创治疗的一种有效选择。