家族性抗磷脂综合征与凝血因子V Leiden共存：对血栓形成素质的影响。
Coexistence of familial antiphospholipid syndrome and factor V Leiden: impact on thrombotic diathesis.
作者信息
Brenner B, Vulfsons S L, Lanir N, Nahir M
机构信息
Department of Internal Medicine D, Rambam Medical Centre, Haifa, Israel.
出版信息
Br J Haematol. 1996 Jul;94(1):166-7. doi: 10.1046/j.1365-2141.1996.d01-1757.x.
Abstract
Two young siblings who presented with an unusual recurrent severe thromboembolic phenomenon were found to have familial anti-phospholipid syndrome and were heterozygous for the factor V R506Q mutation. The coexistence of hereditary and acquired APC-resistance may explain the severity of thromboembolism.
摘要
两名出现异常复发性严重血栓栓塞现象的年轻兄妹被发现患有家族性抗磷脂综合征，并且是因子V R506Q突变的杂合子。遗传性和获得性活化蛋白C抵抗的共存可能解释了血栓栓塞的严重性。
Zotero 插件