Vigotti M A, Rossi G, Bisanti L, Zanobetti A, Schwartz J
Unità di Epidemiologia e Biostatistica, Istituto di Fisiologia Clinica, Pisa, Italy.
J Epidemiol Community Health. 1996 Apr;50 Suppl 1(Suppl 1):s71-5. doi: 10.1136/jech.50.suppl_1.s71.
To investigate the association between daily urban air pollution and acute effects on respiratory health.
Time series analysis following the procedure defined in the APHEA protocol.
City of Milan, Italy, from 1980-89. Two air pollutants, total suspended particulates (TSP) and sulphur dioxide (SO2), and two health outcomes, deaths and hospital admissions were considered. The last was analysed according to two age groups.
Daily deaths and general hospital admissions for respiratory causes in residents who died in Milan or were admitted to local hospitals in that city.
There was an increased risk of respiratory death and of hospital admission associated with increased concentrations of SO2 and TSP. The relative risks were similar for both pollutants, and were higher for respiratory deaths than for hospital admissions. No changes in relation to season were seen in the SO2 effect on respiratory deaths, but there was a suggestion of a higher effect on hospital admissions in the cool months. The seasonal pattern of the TSP effect was inconsistent: for mortality it was higher in the warm period while for hospital admissions it seemed to be higher in the cool months. This last result might be due to chance, although some role could have been played by the hospital admission data on all general admissions for respiratory causes (ICD-9: 460-519) as these are a much less specific end point.
In Milan, a positive association was found between the daily SO2 or TSP concentrations and the number of deaths or hospital admissions for respiratory causes. This confirms results from other European and North American cities.
调查城市每日空气污染与对呼吸健康的急性影响之间的关联。
按照APHEA协议中定义的程序进行时间序列分析。
意大利米兰市,时间跨度为1980 - 1989年。考虑了两种空气污染物,即总悬浮颗粒物(TSP)和二氧化硫(SO₂),以及两种健康结果,即死亡和住院人数。对住院人数按两个年龄组进行了分析。
在米兰死亡或在该市当地医院住院的居民中因呼吸原因导致的每日死亡人数和综合医院住院人数。
SO₂和TSP浓度升高与呼吸死亡风险和住院风险增加相关。两种污染物的相对风险相似,呼吸死亡的相对风险高于住院风险。SO₂对呼吸死亡的影响在季节上没有变化,但在凉爽月份对住院人数的影响似乎更高。TSP影响的季节模式不一致:对于死亡率,在温暖时期较高,而对于住院人数,似乎在凉爽月份较高。最后这个结果可能是偶然的,尽管呼吸原因导致的所有综合住院人数(国际疾病分类第九版:460 - 519)的住院数据可能起到了一定作用,因为这些是一个特异性低得多的终点。
在米兰,发现每日SO₂或TSP浓度与呼吸原因导致的死亡人数或住院人数之间存在正相关。这证实了其他欧洲和北美城市的研究结果。