猪14号染色体的PiGMaP和美国农业部图谱整合

Integration of the PiGMaP and USDA maps for porcine chromosome 14.

作者信息

Kapke P, Wang L, Helm J, Rothschild M F

机构信息

Department of Animal Sciences, Iowa State University, Ames 50011, USA.

出版信息

Anim Genet. 1996 Jun;27(3):187-90. doi: 10.1111/j.1365-2052.1996.tb00949.x.

DOI:10.1111/j.1365-2052.1996.tb00949.x

PMID:8759119

Abstract

In order to align two previously published genetic linkage maps, a set of four of the United States Department of Agriculture (USDA) microsatellite linkage markers was mapped in the International Pig Gene Mapping Project (PiGMaP) reference families. Two-point linkage analysis was used between these USDA markers and the set of genes and markers previously mapped on the PiGMaP chromosome 14 map. Markers with threshold lod scores of three or greater were used for multipoint map construction. The USDA and PigGMaP linkage maps of chromosome 14 were aligned using the four USDA microsatellite markers along with three markers that are common to both maps. The PiGMaP genetic linkage map order for chromosome 14 was confirmed and the map was expanded to 193 cM with addition of the new markers.

摘要

为了比对两张先前发表的遗传连锁图谱，在美国农业部（USDA）的一组四个微卫星连锁标记在国际猪基因图谱计划（PiGMaP）参考家系中进行了定位。在这些USDA标记与先前定位在PiGMaP 14号染色体图谱上的一组基因和标记之间进行了两点连锁分析。阈值对数优势分数为3或更高的标记用于构建多点图谱。利用四个USDA微卫星标记以及两张图谱共有的三个标记，对14号染色体的USDA和PiGMaP连锁图谱进行了比对。确认了PiGMaP 14号染色体的遗传连锁图谱顺序，并通过添加新标记将图谱扩展到了193厘摩。