Waterhouse J, Minors D, Akerstedt T, Hume K, Kerkhof G
School of Biological Sciences, University of Manchester, UK.
Pathol Biol (Paris). 1996 Mar;44(3):205-7.
Measured circadian rhythms consist of endogenous (clock-driven) and exogenous (lifestyle-driven) components. The exogenous components cause difficulties of interpretation of phase and amplitude information. Such effects can be removed by "constant routines", but these protocols are restricted to the laboratory. By contrast, the process of "purification" of circadian rhythms uses the knowledge of an individual's normal lifestyle to separate a measured rhythm into its two components. This method has been shown to be practicable in a variety of circumstances and to provide a feasible alternative to constant routines.
测量到的昼夜节律由内源性（生物钟驱动）和外源性（生活方式驱动）成分组成。外源性成分会给相位和振幅信息的解读带来困难。这种影响可以通过“固定作息”消除，但这些方案仅限于实验室使用。相比之下，昼夜节律“纯化”过程利用个体正常生活方式的知识，将测量到的节律分为两个成分。这种方法已被证明在各种情况下都是可行的，并且为固定作息提供了一种可行的替代方案。
