Michel J L, Guiguen Y, Léger F, Gain P, Valanconny C, Cambazard F
Service de Dermatologie, CHU Saint-Etienne.
Ann Dermatol Venereol. 1996;123(2):90-2.
Human papilloma virus is highly prevalent, but rarely localized in the conjunctiva.
A 19-year-old man with no past history of skin or mucosal disease consulted for tumefaction of the conjunctiva. Exeresis revealed a viral papilloma. In situ hybridization was positive for human papilloma virus 6/11.
Conjunctival lesions of human papilloma virus are often located in the caroncula as in our patient. The papillomatous aspect of the tumour may suggest squamous cell carcinoma (sometimes induced by human papillomavirus 16/18). Contamination may be manual or occur at birth via the maternal genital mucosa. Treatment usually is based on wide exeresis with cryo-application although spontaneous regression is possible.
人乳头瘤病毒非常普遍,但很少局限于结膜。
一名19岁男性,既往无皮肤或黏膜疾病史,因结膜肿胀前来就诊。切除术后发现为病毒性乳头瘤。原位杂交检测人乳头瘤病毒6/11呈阳性。
人乳头瘤病毒引起的结膜病变通常如我们的患者一样位于泪阜。肿瘤的乳头瘤样外观可能提示鳞状细胞癌(有时由人乳头瘤病毒16/18诱发)。感染可能是通过手接触或在出生时通过母体生殖道黏膜发生。治疗通常基于广泛切除并联合冷冻治疗,尽管也有可能自发消退。