Lennox P, Hern J, Birchall M, Lund V
Department of Rhinology, Royal National Throat, Nose and Ear Hospital, London, UK.
J Laryngol Otol. 1996 Jun;110(6):540-2. doi: 10.1017/s0022215100134206.
Flexible nasendoscopy is now an integral part of the diagnostic process in Otorhinolaryngology. Topical local anaesthesia is generally recommended and cocaine is usually the drug of choice in view of its concurrent vasoconstrictor action. However, it is expensive, a controlled drug and serious side effects have been reported. Co-phenylcaine forte is a new preparation which also has both local anaesthetic and vasoconstrictor properties. This study compares the efficacy of cocaine and Co-phenylcaine in flexible nasendoscopy and concludes that they provide similar local anaesthesia and vasoconstriction of the nasal mucosa. Co-phenylcaine forte can therefore be used as an alternative to cocaine in flexible nasendoscopy.
可弯曲鼻内镜检查现已成为耳鼻咽喉科诊断过程中不可或缺的一部分。一般建议采用局部表面麻醉，鉴于可卡因具有同时收缩血管的作用，它通常是首选药物。然而，它价格昂贵，属于管制药品，且有严重副作用的报道。强力复方苯佐卡因是一种新制剂，也具有局部麻醉和血管收缩特性。本研究比较了可卡因和强力复方苯佐卡因在可弯曲鼻内镜检查中的效果，得出它们在鼻黏膜局部麻醉和血管收缩方面效果相似的结论。因此，在可弯曲鼻内镜检查中，强力复方苯佐卡因可作为可卡因的替代品使用。
