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Role of the HAP1 protein in repair of oxidative DNA damage and regulation of transcription factors.

作者信息

Barzilay G, Walker L J, Rothwell D G, Hickson I D

机构信息

Imperial Cancer Research Fund Laboratories, University of Oxford, John Radcliffe Hospital, UK.

出版信息

Br J Cancer Suppl. 1996 Jul;27:S145-50.

PMID:8763868
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2149983/
Abstract
摘要

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Role of the HAP1 protein in repair of oxidative DNA damage and regulation of transcription factors.HAP1蛋白在氧化DNA损伤修复及转录因子调控中的作用。
Br J Cancer Suppl. 1996 Jul;27:S145-50.
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Role of apurinic/apyrimidinic nucleases in the regulation of homologous recombination in myeloma: mechanisms and translational significance.嘌呤/嘧啶核酸内切酶在骨髓瘤中同源重组调控中的作用：机制和转化意义。
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Instability and decay of the primary structure of DNA.DNA一级结构的不稳定性与衰变
Nature. 1993 Apr 22;362(6422):709-15. doi: 10.1038/362709a0.
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Escape from redox regulation enhances the transforming activity of Fos.逃脱氧化还原调节会增强Fos的转化活性。
Oncogene. 1993 Mar;8(3):695-701.
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Oxidants, antioxidants, and the degenerative diseases of aging.氧化剂、抗氧化剂与衰老性退行性疾病
Effect of caloric restriction on base-excision repair (BER) in the aging rat brain.
热量限制对衰老大鼠大脑碱基切除修复（BER）的影响。
Exp Gerontol. 2010 Mar;45(3):208-16. doi: 10.1016/j.exger.2009.12.003. Epub 2009 Dec 11.
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Going ape as an approach to cancer therapeutics.走“疯狂的猩猩”之路治疗癌症。
Antioxid Redox Signal. 2009 Mar;11(3):651-68. doi: 10.1089/ars.2008.2218.
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Structural insights by molecular dynamics simulations into specificity of the major human AP endonuclease toward the benzene-derived DNA adduct, pBQ-C.通过分子动力学模拟对人类主要AP内切核酸酶对苯衍生的DNA加合物pBQ-C的特异性的结构见解。
Nucleic Acids Res. 2004 May 20;32(9):2844-52. doi: 10.1093/nar/gkh594. Print 2004.
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A novel fluorometric oligonucleotide assay to measure O( 6)-methylguanine DNA methyltransferase, methylpurine DNA glycosylase, 8-oxoguanine DNA glycosylase and abasic endonuclease activities: DNA repair status in human breast carcinoma cells overexpressing methylpurine DNA glycosylase.一种用于测量O(6)-甲基鸟嘌呤DNA甲基转移酶、甲基嘌呤DNA糖基化酶、8-氧代鸟嘌呤DNA糖基化酶和无碱基内切核酸酶活性的新型荧光寡核苷酸检测法：过表达甲基嘌呤DNA糖基化酶的人乳腺癌细胞中的DNA修复状态
Nucleic Acids Res. 2001 Jun 15;29(12):2558-66. doi: 10.1093/nar/29.12.2558.
7
Expression levels of the DNA repair enzyme HAP1 do not correlate with the radiosensitivities of human or HAP1-transfected rat cell lines.DNA修复酶HAP1的表达水平与人类或HAP1转染的大鼠细胞系的放射敏感性无关。
Br J Cancer. 1999 Jun;80(7):940-5. doi: 10.1038/sj.bjc.6690447.
Proc Natl Acad Sci U S A. 1993 Sep 1;90(17):7915-22. doi: 10.1073/pnas.90.17.7915.
4
Identification of residues in the human DNA repair enzyme HAP1 (Ref-1) that are essential for redox regulation of Jun DNA binding.鉴定人类DNA修复酶HAP1（Ref-1）中对Jun DNA结合的氧化还原调节至关重要的残基。
Mol Cell Biol. 1993 Sep;13(9):5370-6. doi: 10.1128/mcb.13.9.5370-5376.1993.
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The c-Myc protein induces cell cycle progression and apoptosis through dimerization with Max.c-Myc蛋白通过与Max二聚化诱导细胞周期进程和细胞凋亡。
EMBO J. 1993 Dec 15;12(13):5083-7. doi: 10.1002/j.1460-2075.1993.tb06202.x.
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The control of apoptosis in mammalian cells.哺乳动物细胞中细胞凋亡的调控
Trends Biochem Sci. 1993 Aug;18(8):307-9. doi: 10.1016/0968-0004(93)90042-l.
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Activation of AP-1 and of a nuclear redox factor, Ref-1, in the response of HT29 colon cancer cells to hypoxia.HT29结肠癌细胞在低氧反应中AP-1和核氧化还原因子Ref-1的激活。
Mol Cell Biol. 1994 Sep;14(9):5997-6003. doi: 10.1128/mcb.14.9.5997-6003.1994.
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Repair of oxidative damage to DNA: enzymology and biology.DNA氧化损伤的修复：酶学与生物学
Annu Rev Biochem. 1994;63:915-48. doi: 10.1146/annurev.bi.63.070194.004411.
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Structure and function of the multifunctional DNA-repair enzyme exonuclease III.多功能DNA修复酶外切核酸酶III的结构与功能
Nature. 1995 Mar 23;374(6520):381-6. doi: 10.1038/374381a0.
10
Mechanisms and genes of cellular suicide.细胞自杀的机制与基因
Science. 1995 Mar 10;267(5203):1445-9. doi: 10.1126/science.7878463.