Collins M K, Lopez Rivas A
Chester Beatty Laboratories, Institute of Cancer Research, London, UK.
Trends Biochem Sci. 1993 Aug;18(8):307-9. doi: 10.1016/0968-0004(93)90042-l.
This article summarizes what is now known, more than 100 years after this prescient observation, of the mechanisms by which death of mammalian cells is regulated. Particular attention is paid to the elimination of self-reactive thymocytes, the induction of cell death during cancer therapy and the mechanism(s) by which cells die following growth factor removal.
本文总结了在这一有先见之明的观察发表100多年后，目前已知的哺乳动物细胞死亡调控机制。特别关注了自身反应性胸腺细胞的清除、癌症治疗过程中细胞死亡的诱导以及细胞在生长因子去除后死亡的机制。
