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白内障手术中表面麻醉与球后麻醉的比较。

A comparison of topical and retrobulbar anesthesia for cataract surgery.

作者信息

Patel B C, Burns T A, Crandall A, Shomaker S T, Pace N L, van Eerd A, Clinch T

机构信息

John A. Moran Eye Center, University of Utah School of Medicine, Salt Lake City 84132, USA.

出版信息

Ophthalmology. 1996 Aug;103(8):1196-203. doi: 10.1016/s0161-6420(96)30522-8.

Abstract

PURPOSE

To evaluate and compare the efficacy of topical and retrobulbar anesthesia for cataract extraction with intraocular lens implantation.

METHODS

One hundred thirty-eight patients prospectively were assigned to the topical (group 1; n = 69) or retrobulbar (group 2; n = 69) anesthesia groups by permuted block restricted randomization. Group 1 received topical 0.75% bupivacaine and intravenous midazolam and fentanyl for anesthesia. Group 2 received intravenous methohexital followed by retrobulbar block with an equal mixture of 2% lidocaine and 0.75% bupivacaine plus hyaluronidase (150 U). A visual pain analogue scale was used to assess the degree of pain during the administration of anesthesia, during surgery, and post-operatively. The degree to which eye movement, touch, and light caused patient discomfort was assessed. Complications and surgical conditions were recorded.

RESULTS

There was no difference in the surgical conditions (P = 0.5) or pain during surgery (P = 0.35) between the two groups. There was more discomfort during administration of topical anesthesia (P < 0.0001) and postoperatively (P < 0.05) in the topical group. Chemosis, subconjunctival hemorrhage, and eyelid hemorrhage were seen almost exclusively in the retrobulbar group. One patient in group 2 had a retrobulbar hemorrhage. Although eyeball movement and squeezing of the eyelids were present more frequently in the topical group, neither was a problem to the surgeon.

CONCLUSION

Topical anesthesia can be used safely for cataract extraction. The degree of patient discomfort is only marginally higher during administration of the anesthesia and postoperatively. However, surgical training and patient preparation are the keys to the safe use of topical anesthesia.

摘要

目的

评估并比较表面麻醉与球后麻醉用于白内障摘除联合人工晶状体植入术的疗效。

方法

138例患者通过置换区组受限随机化法前瞻性地分为表面麻醉组(第1组;n = 69)和球后麻醉组(第2组;n = 69)。第1组接受0.75%布比卡因表面麻醉以及静脉注射咪达唑仑和芬太尼进行麻醉。第2组先静脉注射美索比妥,随后行球后阻滞,使用2%利多卡因和0.75%布比卡因加透明质酸酶(150 U)的等量混合液。采用视觉模拟疼痛量表评估麻醉给药期间、手术期间及术后的疼痛程度。评估眼球运动、触摸及光线导致患者不适的程度。记录并发症及手术情况。

结果

两组的手术情况(P = 0.5)及手术期间疼痛程度(P = 0.35)无差异。表面麻醉组在表面麻醉给药期间(P < 0.0001)及术后(P < 0.05)有更多不适。结膜水肿、结膜下出血及眼睑出血几乎仅见于球后麻醉组。第2组有1例患者发生球后出血。尽管表面麻醉组眼球运动及眼睑挤压更频繁出现,但对术者而言均不是问题。

结论

表面麻醉可安全用于白内障摘除术。患者不适程度仅在麻醉给药期间及术后略高。然而,手术培训及患者准备是安全使用表面麻醉的关键。

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