急性氯丙嗪摄入导致的上气道梗阻

Upper airway compromise in acute chlorpromazine ingestion.

作者信息

Russell S A, Hennes H M, Herson K J, Stremski E S

机构信息

Medical College of Wisconsin, Milwaukee, USA.

出版信息

Am J Emerg Med. 1996 Sep;14(5):467-8. doi: 10.1016/S0735-6757(96)90154-0.

DOI:10.1016/S0735-6757(96)90154-0

PMID:8765112

Abstract

A 16-year-old boy developed symptoms of acute upper airway compromise after chlorpromazine ingestion. The patient took six 100-mg Thorazine tablets "to help him sleep". Laryngeal-pharyngeal dystonia is a life-threatening form of dystonic reaction that is dose-dependent. In children, acute upper airway compromise should raise the suspicion of exposure to phenothiazines.

摘要

一名16岁男孩在服用氯丙嗪后出现急性上呼吸道梗阻症状。该患者服用了六片100毫克的氯丙嗪片（商品名：冬眠灵）“助眠”。喉咽肌张力障碍是一种危及生命的肌张力障碍反应形式，与剂量相关。在儿童中，急性上呼吸道梗阻应引起对吩噻嗪类药物暴露的怀疑。