Hyams J S, Burke G, Davis P M, Rzepski B, Andrulonis P A
Department of Pediatrics, Hartford Hospital, Connecticut Children's Medical Center 06106, USA.
J Pediatr. 1996 Aug;129(2):220-6. doi: 10.1016/s0022-3476(96)70246-9.
This study was undertaken to determine (1) the prevalence of gastrointestinal symptoms including abdominal pain in a community-based population of adolescents, (2) whether a subgroup of these subjects have symptoms resembling Irritable bowel syndrome (IBS), and (3) whether anxiety and depression are more commonly found in adolescents with IBS-type symptoms compared with unaffected adolescents.
We collected data by administration of a gastrointestinal symptoms questionnaire, State-Trait Anxiety Inventory, and Children's Depression Inventory to middle school and high school students.
A total of 507 subjects participated (mean age of middle school students 12.6 years; mean age of high school students 15.6 years). Abdominal pain was noted by 75% of all students. The pain occurred weekly in 13% to 17% of the subjects and was severe enough to affect activities in approximately 21%. Irritable bowel syndrome-type symptoms were noted by 17% of high school students and 8% of middle school students (p <0.01) who reported abdominal pain (n = 381), representing 14% and 6% of all high school and middle school students (p <0.005), respectively. Anxiety and depression scores were significantly higher for students with IBS-type symptoms compared with those without symptoms. Eight percent of all students had seen a physician for abdominal pain in the previous year. These visits were correlated with abdominal pain severity, frequency, duration, and disruption of normal activities but not with anxiety, depression, gender, family structure, or ethnicity.
Recurrent abdominal pain and symptoms of IBS are commonly noted in a community-based adolescent population and frequently result in use of health care resources. Health care providers who work with this age group need to be able to recognize the symptom complex associated with IBS, as well as the possible relationship to anxiety and depression.
本研究旨在确定（1）以社区为基础的青少年人群中胃肠道症状（包括腹痛）的患病率；（2）这些受试者中是否有一部分人的症状类似于肠易激综合征（IBS）；（3）与未受影响的青少年相比，患有IBS型症状的青少年中焦虑和抑郁是否更常见。
我们通过向初中和高中学生发放胃肠道症状问卷、状态-特质焦虑量表和儿童抑郁量表来收集数据。
共有507名受试者参与（初中生平均年龄12.6岁；高中生平均年龄15.6岁）。所有学生中有75%注意到腹痛。13%至17%的受试者每周都会出现腹痛，且疼痛严重到足以影响约21%的人的活动。报告腹痛的高中生中有17%、初中生中有8%出现了肠易激综合征型症状（p<0.01），分别占所有高中生和初中生的14%和6%（p<0.005）。与没有症状的学生相比，患有IBS型症状的学生的焦虑和抑郁得分显著更高。所有学生中有8%的人在上一年因腹痛看过医生。这些就诊与腹痛的严重程度、频率、持续时间以及正常活动的中断有关，但与焦虑、抑郁、性别、家庭结构或种族无关。
在以社区为基础的青少年人群中，反复出现的腹痛和IBS症状很常见，并经常导致医疗资源的使用。与这个年龄段人群打交道的医疗服务提供者需要能够识别与IBS相关的症状复合体，以及与焦虑和抑郁的可能关系。
