[实验性静脉阻塞后视网膜一氧化氮释放的早期变化]
[Early alterations in release of nitrogen monoxide by the retinal after experimental venous occlusion].
作者信息
Donati G, Pournaras C J, Kalogeropoulos C, Munoz J L, Dimitracos S, Pizzolato G P, Tsacopoulos M
机构信息
Clinique d'Ophtalmologie, HCUG.
出版信息
Klin Monbl Augenheilkd. 1996 May;208(5):373-4. doi: 10.1055/s-2008-1035244.
PURPOSE
We present hereby some results indicating that there is a significant decrease in the release of NO by the retina immediately after branch-venous occlusion (BVO).
METHODS
Using an NO microprobe we measured (NO) in the preretinal vitreous of miniature pigs before and two hours aRer bvo. Conventional and electronic microscopy were performed on the affected retina.
RESULTS
At the retinal surface (NO) was reduced to 25% of the previous value two hours after BVO, at the same time significative oedema of the inner retina was observed.
CONCLUSIONS
Immediately after BVO there is a significative decrease in the amount of NO released by the affected retina, parallel to the first evidences of an oedema of the inner retinal layers.
目的
我们在此展示一些结果，表明分支静脉阻塞（BVO）后视网膜立即释放的一氧化氮（NO）显著减少。
方法
使用NO微探针，我们在小型猪的视网膜前玻璃体中，于BVO前及之后两小时测量（NO）。对受影响的视网膜进行传统显微镜检查和电子显微镜检查。
结果
在视网膜表面，BVO后两小时（NO）降至先前值的25%，同时观察到视网膜内层有明显水肿。
结论
BVO后，受影响的视网膜释放的NO量显著减少，这与视网膜内层水肿的最初迹象同时出现。
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