Jurado M A, Junqué C
Departmento de Psiquiatría y Psicobiología Clínica, Universidad de Barcelona.
Actas Luso Esp Neurol Psiquiatr Cienc Afines. 1996 May-Jun;24(3):148-55.
We review the main experimental works about the relationship between psychopathy and prefrontal cortex. First neuropsychological articles found contradictory results exploring psychopaths who were diagnosed by different criteria and using putative dorsolateral tests. Attentional deficits in psychopaths and relationships between psychopathy and attention disorder with and without hyperactivity have been studied. Distinction between primary and secondary psychopathy has been related to neuropsychological impairment in antisocial disorder. Differentiation between orbital and dorsolateral prefrontal systems should be taken into account in order to study the neuropsychological deficits in psychopathy. It has been pointed that orbitoventral system would be involved in antisocial behaviour. Hence, neuropsychological impairment in psychopaths is expected to be related to orbitofrontal dysfunction.
我们回顾了关于精神变态与前额叶皮层之间关系的主要实验研究。首先，神经心理学文章在探索被不同标准诊断出的精神变态者并使用假定的背外侧测试时发现了相互矛盾的结果。已经对精神变态者的注意力缺陷以及精神变态与有无多动的注意力障碍之间的关系进行了研究。原发性和继发性精神变态之间的区别与反社会障碍中的神经心理学损害有关。为了研究精神变态中的神经心理学缺陷，应考虑眶额和背外侧前额叶系统之间的差异。有人指出，眶腹系统会参与反社会行为。因此，预计精神变态者的神经心理学损害与眶额功能障碍有关。
