[播散性曲霉病和毛霉病。病例报告]

[Disseminated aspergillosis and mucormycosis. A case report].

作者信息

Mölle M, Blaschke-Hellmessen R, Schuler U, Nowak R, Ehninger G

机构信息

Medizinische Klinik, Universitätsklinikum Carl Gustav Carus, Technischen Universität Dresden, Deutschland.

出版信息

Mycoses. 1996;39 Suppl 1:59-64. doi: 10.1111/j.1439-0507.1996.tb00507.x.

DOI:10.1111/j.1439-0507.1996.tb00507.x

PMID:8767273

Abstract

This paper reports a simultaneous pulmonary infection due to Aspergillus fumigatus and Rhizomucor pusillus which evolved to disseminated aspergillosis and mucormycosis in a leukaemic and neutropenic 40-year-old woman. Both fungi were cultured ante mortem from bronchial secretion. Although high doses of intravenous amphotericin B were administered, the course of the infection was fatal. At autopsy, aspergilli were demonstrated by histology in lungs and brain, and zygomycetes were found to have invaded liver and kidneys.

摘要

本文报道了一名40岁白血病且中性粒细胞减少的女性同时感染烟曲霉和微小根毛霉，进而发展为播散性曲霉病和毛霉病。两种真菌均在生前从支气管分泌物中培养出来。尽管给予了高剂量的静脉注射两性霉素B，但感染过程仍为致命性。尸检时，通过组织学在肺和脑中发现了曲霉菌，并且发现接合菌已侵入肝脏和肾脏。