Wendum D, Sautet A, Prévot S, Martel D, Apoil A, de Saint Maur P P
Service Central d'Anatomie et Cytologie Pathologiques, Hôpital Saint-Antoine, Paris.
Ann Pathol. 1996;16(2):115-9.
Primary leiomyosarcoma of bone is rare. Herein we describe 3 cases with immunohistochemical study. All 3 cases were positive for smooth muscle actin and/or desmin. None was positive for cytokeratin. Differential diagnosis includes metastatic spindle cell carcinoma, other sarcoma (fibrosarcoma, malignant fibrous histiocytoma) and metastatic extra-osseous leiomyosarcoma, mostly from uterus or digestive tract.
原发性骨平滑肌肉瘤罕见。在此我们描述3例并进行免疫组化研究。所有3例平滑肌肌动蛋白和/或结蛋白均呈阳性。细胞角蛋白均为阴性。鉴别诊断包括转移性梭形细胞癌、其他肉瘤(纤维肉瘤、恶性纤维组织细胞瘤)以及转移性骨外平滑肌肉瘤,后者大多来源于子宫或消化道。