Erhard M H, Bergmann J, Renner M, Hofmann A, Heinritzi K
Institut für Physiologie, Physiologische Chemie und Tierernährung, Tierärztlichen Fakultät, Ludwig-Maximilians-Universität München, Deutschland.
Zentralbl Veterinarmed A. 1996 Jun;43(4):217-23.
In this study, the protective effect of specific egg yolk antibodies on diarrhea caused by Escherichia coli K88 (F4) was investigated with 179 weaning piglets in a double-blind field trial. The piglets were divided into three groups. The antibody group received egg powder with specific antibodies to E. coli K88, K99, 987P, and rotavirus, while one control group was fed with egg powder without specific antibodies and a second control group received no egg powder at all. The piglets were fed ad libitum. The egg powder was offered in a 5% feed ration. Compared with the control groups, the piglets of the antibody group showed significant differences (P < 0.05, chi 2-test) in the parameters rate of diarrhea (17.2%) (antibody group) to 60.7% (control egg group) or 56.7% (control group without egg powder), severity of symptoms (5.2-39.3% or 26.7%) and frequency of additional treatments (8.6-55.7% or 51.7%). Because of the additional treatments, no difference could be found in body-weight gain. In control groups, three piglets died, while no pigs died in the antibody group.
在本研究中，使用179头断奶仔猪进行双盲田间试验，研究了特异性蛋黄抗体对大肠杆菌K88（F4）引起的腹泻的保护作用。仔猪被分为三组。抗体组接受含有针对大肠杆菌K88、K99、987P和轮状病毒的特异性抗体的蛋粉，而一个对照组喂食不含特异性抗体的蛋粉，另一个对照组根本不喂蛋粉。仔猪自由采食。蛋粉以5%的饲料比例提供。与对照组相比，抗体组仔猪在腹泻发生率（17.2%）（抗体组）与60.7%（对照蛋粉组）或56.7%（无蛋粉对照组）、症状严重程度（5.2 - 39.3%或26.7%）以及额外治疗频率（8.6 - 55.7%或51.7%）等参数上显示出显著差异（P < 0.05，卡方检验）。由于额外治疗，在体重增加方面未发现差异。在对照组中，有3头仔猪死亡，而抗体组无仔猪死亡。
