Strittmatter M, Zimmermann C, Schimrigk K, Hamann G F
Abteilung Neurologie, Universität des Saarlandes, Homburg, Bundesrepublik Deutschland.
Wien Klin Wochenschr. 1996;108(11):326-9.
Acute severe headache indicative of subarachnoid haemorrhage (SAH), but without the requisite proof, is defined as thunderclap. A special pathophysiological mechanism for the development of this headache is not known as yet. This retrospective study comprised 84 patients. All had the typical clinical signs of a SAH, but cranial computer tomography and lumbar puncture excluded this diagnosis. In 82% of these patients the headache was classified according to aetiologically defined symptomatic groups. One patient with headache of vascular aetiology had an angiographically proven, but not ruptured aneurysm. No definite cause for the headache was found in 18% of cases. None of the patients followed up over a period of between 12 months and 6 years developed SAH or any other severe neurological disorder. 9% reported repeat of the headache event. Thunderclap headache seems to be only a descriptive term for patients with symptoms typical of a SAH without signs of bleeding. Thunderclap headache has no diagnostic or prognostic specificity and therefore we recommend use of this term only as a description of the headache characteristic. Thunderclap headache is not a predictor of a future SAH. Cerebral angiography should be restricted to cases with neurological deficits.
提示蛛网膜下腔出血(SAH)但缺乏必要证据的急性重度头痛被定义为霹雳性头痛。目前尚不清楚这种头痛发展的特殊病理生理机制。这项回顾性研究纳入了84例患者。所有患者均有SAH的典型临床体征,但头颅计算机断层扫描和腰椎穿刺排除了该诊断。在这些患者中,82%的头痛根据病因明确的症状组进行了分类。1例血管性病因头痛患者经血管造影证实有未破裂的动脉瘤。18%的病例未发现头痛的确切病因。在随访12个月至6年的患者中,无一例发生SAH或任何其他严重神经系统疾病。9%的患者报告头痛事件复发。霹雳性头痛似乎只是对具有SAH典型症状但无出血迹象患者的一种描述性术语。霹雳性头痛没有诊断或预后特异性,因此我们建议仅将该术语用作头痛特征的描述。霹雳性头痛不是未来SAH的预测指标。脑血管造影应仅限于有神经功能缺损的病例。