Pederzoli P, Bassi C, Falconi M, De Santis L, Bonora A, Salvia R, Caldiron E, Sartori N, Butturini G, Briani G
Dipartimento di Scienze Chirurgiche, Chirurgia Generale B, Policlinico, Università degli Studi, Verona.
Chir Ital. 1995;47(2):30-4.
Between 1976 and 1994, 318 patients underwent surgical closed retro-endoperitoneal drainage and post-operative lavage for acute necrotizing severe pancreatitis. The main indication was sepsis (66.4%). The ratio between operated on and the overall number of observed patients has been progressively shifting towards medical treatment. Furthermore in the operated group the timing of surgery has been delayed step by step. The Authors discuss improvements in the understanding of the etiological and therapeutical aspects of the disease which has had a better outcome in recent years, survival rate of 91.4%. The personal option for the closed surgical approach is based on the progressive improvement of the technique and on the good results obtained both in terms of mortality and associated morbidity; as regards the latter problem the open techniques seems to be related to a higher complication rate than the closed one.
1976年至1994年间,318例患者因急性坏死性重症胰腺炎接受了手术闭式腹膜后引流及术后灌洗治疗。主要指征为脓毒症(66.4%)。接受手术治疗的患者与观察到的患者总数之比已逐渐转向内科治疗。此外,在手术组中,手术时机也在逐步推迟。作者讨论了近年来对该疾病病因和治疗方面认识的改进,其预后较好,生存率为91.4%。选择闭式手术方法的依据是该技术的逐步改进以及在死亡率和相关发病率方面均取得了良好效果;关于后一个问题,开放式技术似乎比闭式技术的并发症发生率更高。