人参细胞培养对洋地黄毒苷元的生物转化

Biotransformation of digitoxigenin by cultured ginseng cells.

作者信息

Kawaguchi K, Watanabe T, Hirotani M, Furuya T

机构信息

School of Pharmaceutical Sciences, Kitasato University, Kanagawa, Japan.

出版信息

Phytochemistry. 1996 Jun;42(3):667-9. doi: 10.1016/0031-9422(96)00079-9.

DOI:10.1016/0031-9422(96)00079-9

PMID:8768321

Abstract

Nine compounds, including a new compound (digitoxigenin beta-D-glucoside malonyl ester), were isolated as biotransformation products of digitoxigenin by cell suspension cultures of Panax ginseng (Pg-3 cell line). At the same time, two known products were identified by TLC and HPLC.

摘要

通过人参（Pg-3细胞系）的细胞悬浮培养，从洋地黄毒苷的生物转化产物中分离出9种化合物，包括一种新化合物（洋地黄毒苷元β-D-葡萄糖苷丙二酸酯）。同时，通过薄层色谱法（TLC）和高效液相色谱法（HPLC）鉴定出两种已知产物。