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[The effect of benzylpenicillin and doxycycline on toxicity and antineoplastic action of cyclophosphamide and methotrexate in mice].

作者信息

Pakulska W

机构信息

Zakład Farmakodynamiki, Katedra Farmakologii, Akademia Medyczna, Lódź.

出版信息

Acta Pol Pharm. 1992;49(1-2):35-40.

PMID:8769079
Abstract

The effect of benzylpenicillin and doxycycline on toxicity and anticancer activity of cyclophosphamide and methotrexate in mice was studied. Benzylpenicillin applied both at once repeatedly enhances anticancer activity of cyclophosphamide against L 1210 leukemia within limited range of CP. Benzylpenicillin does not change anticancer activity of methotrexate, but doxycycline of both cyclophosphamide and methotrexate, against L 1210 leukemia in mice.

摘要

相似文献

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Acta Pol Pharm. 1992;49(1-2):35-40.
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