Lafer B, Nierenberg A A, Rosenbaum J F, Fava M
Depression Research Program, Massachusetts General Hospital, Boston 02114, USA.
Compr Psychiatry. 1996 Jan-Feb;37(1):37-9. doi: 10.1016/s0010-440x(96)90048-6.
The purpose of this study was to compare outpatients who met DSM-III-R versus DSM-IV criteria for melancholia. Of 176 consecutive outpatients with unipolar depression, 40 (22.7%) met DSM-III-R criteria and 29 (16.5%) met DSM-IV criteria for melancholia. Patients with DSM-IV melancholia had higher mean scores on measurements of clinical severity as compared with those who qualified for a DSM-III-R diagnosis. These results suggest that the criteria for melancholia proposed in the DSM-IV are more restrictive and define a more severely depressed population than criteria in the DSM-III-R.
本研究的目的是比较符合《精神疾病诊断与统计手册》第三版修订本(DSM-III-R)与《精神疾病诊断与统计手册》第四版(DSM-IV)中忧郁症标准的门诊患者。在176例连续性单相抑郁症门诊患者中,40例(22.7%)符合DSM-III-R忧郁症标准,29例(16.5%)符合DSM-IV忧郁症标准。与符合DSM-III-R诊断标准的患者相比,符合DSM-IV忧郁症标准的患者在临床严重程度测量上的平均得分更高。这些结果表明,DSM-IV中提出的忧郁症标准比DSM-III-R中的标准更具限制性,且定义的是病情更严重的抑郁人群。