Laidlaw T M, Booth R J, Large R G
Department of Psychiatry and Behavioral Science, School of Medicine, University of Auckland, New Zealand.
Psychosom Med. 1996 May-Jun;58(3):242-8. doi: 10.1097/00006842-199605000-00008.
This study sought to test whether a cognitive-hypnotic intervention could be used to decrease skin reactivity to histamine and whether hypnotizability, physiological variables, attitudes, and mood would influence the size of the skin weals. Thirty eight subjects undertook three individual laboratory sessions; a pretest session to determine sensitivity to histamine, a control session, and an intervention session during which the subject experienced a cognitive-hypnotic procedure involving imagination and visualization. Compared with the control session, most subjects (32 of 38) decreased the size of their weals measured during the intervention session, and the differences between the weal sizes produced in the two sessions were highly significant (N = 38; t = 4.90; p < .0001). Mood and physiological variables but not hypnotizability scores proved to be effective in explaining the skin test variance and in predicting weal size change. Feelings of irritability and tension and higher blood pressure readings were associated with less change in weal size (i.e., a continuation of reactivity similar to that found in the control session without the cognitive-hypnotic intervention), and peacefulness and a lower blood pressure were associated with less skin reactivity during the intervention. This study has shown highly significant results in reducing skin sensitivity to histamine using a cognitive-hypnotic technique, which indicates some promise for extending this work into the clinical area.
本研究旨在测试认知催眠干预是否可用于降低皮肤对组胺的反应性，以及催眠易感性、生理变量、态度和情绪是否会影响皮肤风团的大小。38名受试者参加了三次个人实验室测试；一次预测试以确定对组胺的敏感性，一次对照测试，以及一次干预测试，在此期间受试者经历了一个涉及想象和可视化的认知催眠程序。与对照测试相比，大多数受试者（38名中的32名）在干预测试期间测量的风团大小减小，两次测试产生的风团大小差异非常显著（N = 38；t = 4.90；p < .0001）。情绪和生理变量而非催眠易感性得分被证明能有效解释皮肤测试差异并预测风团大小变化。易怒和紧张情绪以及较高的血压读数与风团大小变化较小相关（即，类似于在没有认知催眠干预的对照测试中发现的反应性持续存在），而平静和较低的血压与干预期间较低的皮肤反应性相关。本研究表明，使用认知催眠技术降低皮肤对组胺的敏感性取得了非常显著的结果，这表明将这项工作扩展到临床领域具有一定的前景。
