Riabov S I, Rakitianskaia I A, Stavskaia V V, Nikitina N A
Ter Arkh. 1996;68(6):24-7.
Before starting treatment of chronic glomerulonephritis it is desirable to determine the patient's drug sensitivity in vitro because in the absence of such sensitivity chemotherapy should be preceded by immunomodulation with tactivin or thymalin and 3-5 sessions of plasmapheresis to stimulate drug sensitivity. Further measures include prednisolone or cyclophosphamide intravenously for 3-5 days in a dose 300-500 followed by oral administration. Active treatment lasts for 4-8 weeks. After that the patients receive maintenance for 1-2 years.
在开始治疗慢性肾小球肾炎之前，最好先在体外确定患者的药物敏感性，因为如果缺乏这种敏感性，在化疗之前应先用促生素或胸腺素进行免疫调节，并进行3 - 5次血浆置换以刺激药物敏感性。进一步的措施包括静脉注射泼尼松龙或环磷酰胺3 - 5天，剂量为300 - 500，随后改为口服。积极治疗持续4 - 8周。之后患者接受维持治疗1 - 2年。
