怀卡托医院银屑病紫外线治疗综述。
A review of ultraviolet treatment for psoriasis at Waikato Hospital.
作者信息
Oakley A M, Wyllie K
机构信息
Department of Dermatology, Waikato Hospital, Hamilton, New Zealand.
出版信息
Australas J Dermatol. 1996 Aug;37(3):132-6. doi: 10.1111/j.1440-0960.1996.tb01030.x.
Details of 79 courses of UVB and 40 courses of PUVA for patients with chronic plaque psoriasis at Waikato Hospital were prospectively collected when a new Phototherapy Unit opened. Efficacy was assessed by clearance rates (73% for UVB, 87.5% for PUVA). There was significant improvement in Psoriasis Disability Index, which was derived from a questionnaire assessing functional disability and completed by the patients before and after treatment. It took a median number of 24 treatments for psoriasis in the patients receiving UVB to clear, and for the PUVA patients the median was 19 treatments. The efficacy could not be correlated with skin type. Fifty per cent of UVB patients and 25% of PUVA patients received symptomatic burns, all localized and minor in nature. LIfetime PUVA dose was calculated, 90% of patients having received less than 400 J/cm2.
怀卡托医院新开设光疗科时，前瞻性收集了79例慢性斑块状银屑病患者接受UVB治疗的79个疗程及40例接受PUVA治疗的40个疗程的详细信息。通过清除率评估疗效（UVB为73%，PUVA为87.5%）。银屑病残疾指数有显著改善，该指数来自一份评估功能残疾的问卷，由患者在治疗前后填写。接受UVB治疗的患者银屑病清除的中位治疗次数为24次，接受PUVA治疗的患者中位治疗次数为19次。疗效与皮肤类型无关。50%的UVB患者和25%的PUVA患者出现有症状的烧伤，均为局限性且程度较轻。计算了PUVA的终生剂量，90%的患者接受的剂量小于400 J/cm²。
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