Toone B K, Fenton G W
Psychol Med. 1977 May;7(2):265-70. doi: 10.1017/s0033291700029354.
On the basis of information abstracted from case histories, 41 patients who had experienced epileptic seizures thought to be due either to treatment with psychiatric drugs or to withdrawal from sedative drugs were compared with a control group of patients. Those who had experienced seizures were more commonly first born and had a history of post-natal brain damage. During the week preceding the seizure there had been a marked increase in drug prescribing. The implications for drug management are discussed.
根据从病历中提取的信息，将41例经历过癫痫发作（被认为要么是由精神科药物治疗引起，要么是因停用镇静药物所致）的患者与一组对照患者进行了比较。经历过癫痫发作的患者更常见于头胎出生，并有产后脑损伤史。在癫痫发作前一周，药物处方量显著增加。文中讨论了对药物管理的影响。
