Kaur U, Sahni S P, Bambery P, Kumar B, Chauhan A, Chawla Y K, Dilawari J B
Department of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Natl Med J India. 1996 Jul-Aug;9(4):156-9.
The relationship of hepatitis B virus infection with drug use and sexual activity in Indian college students has not been studied earlier.
We studied this relationship in Chandigarh, using a prospective, cross-sectional questionnaire-based survey and blood tests for hepatitis B markers. The responders were assured of the confidentiality of their responses and blood test results.
Of the 1311 students who participated, 192 (15%) were sexually active. Eight-four per cent of them were heterosexual, 7.3% homosexual and 8.7% bisexual. Thirty-seven per cent of heterosexuals and 36% of homosexuals had more than one partner. Condoms were used by 24% heterosexuals, 11% bisexuals and 7% homosexuals. Of the sera tested, 2.9% were hepatitis B surface antigen positive and 10.4% were positive for the antibody to hepatitis B surface antigen. Fifteen per cent consumed alcohol, but only 1.6% were addicted to other drugs. Two students were intravenous drug users. Eleven per cent had donated blood at least once and a third of these had suffered from jaundice in the past.
The pattern of sexual behaviour, low condom use and the small but definite prevalence of hepatitis B virus infection in this population of students suggests that the human immunodeficiency virus infection may spread rapidly when it enters this community.
此前尚未对印度大学生中乙型肝炎病毒感染与药物使用及性行为之间的关系进行研究。
我们在昌迪加尔开展了此项研究，采用基于问卷调查的前瞻性横断面研究以及乙型肝炎标志物血液检测。研究向应答者保证其回答及血液检测结果将予以保密。
在参与研究的1311名学生中，192人（15%）有性行为。其中84%为异性恋，7.3%为同性恋，8.7%为双性恋。37%的异性恋者和36%的同性恋者有不止一个性伴侣。24%的异性恋者、11%的双性恋者和7%的同性恋者使用避孕套。在检测的血清中，2.9%乙型肝炎表面抗原呈阳性，10.4%乙型肝炎表面抗体呈阳性。15%的学生饮酒，但只有1.6%对其他药物成瘾。两名学生为静脉吸毒者。11%的学生至少献血过一次，其中三分之一曾患黄疸。
该学生群体的性行为模式、避孕套使用率低以及乙型肝炎病毒感染虽比例小但确切存在，表明人类免疫缺陷病毒感染一旦传入该群体可能迅速传播。
