Barton P P, Waneck R E, Karnel F J, Ritschl P, Kramer J, Lechner G L
Department of Radiology, University of Vienna Medical School, Austria.
J Vasc Interv Radiol. 1996 Jan-Feb;7(1):81-8. doi: 10.1016/s1051-0443(96)70738-8.
To assess the effectiveness and clinical usefulness of transcatheter embolization of bone metastases.
The procedures and outcome of 61 transcatheter embolization procedures performed in 51 patients with hypervascular skeletal metastases were retrospectively evaluated. Results from computed tomography, magnetic resonance imaging, and diagnostic angiography, performed before and after embolization, were reviewed.
All embolizations were technically and clinically successful. Major blood loss during surgery was prevented in 32 cases; the size of viable tumor tissue in large, unresectable bone metastases was reduced before radiation or chemotherapy in 17 cases; and otherwise untreatable skeletal pain was decreased in 11 cases. Heavy bleeding from a metastasis was controlled in one case. The complications were temporary paresis of a lower extremity in three patients, cardiac arrest in one patients, and unintentional embolization of synthetic tissue adhesive in one patient. Median survival time was 28 months (range, 3-59 months).
Transcatheter embolization is effective and reliable in the treatment of bone metastases.
评估经导管栓塞治疗骨转移瘤的有效性及临床实用性。
回顾性评估了51例患有富血管性骨转移瘤的患者所接受的61次经导管栓塞治疗的过程及结果。对栓塞前后进行的计算机断层扫描、磁共振成像及诊断性血管造影结果进行了回顾。
所有栓塞治疗在技术和临床方面均获成功。32例患者术中大出血得以避免；17例不可切除的大型骨转移瘤患者在放疗或化疗前，其存活肿瘤组织体积缩小；11例患者原本无法治疗的骨痛减轻。1例转移瘤大出血得到控制。并发症包括3例患者出现下肢暂时麻痹，1例患者心脏骤停，1例患者合成组织黏合剂意外栓塞。中位生存时间为28个月（范围3 - 59个月）。
经导管栓塞治疗骨转移瘤有效且可靠。
