Sasagawa I, Nakada T, Kubota Y, Ishigooka M, Hashimoto T, Sawamura T, Tateno T
Department of Urology, Yamagata University, Japan.
Int Urol Nephrol. 1995;27(5):585-91. doi: 10.1007/BF02564745.
Hormonal and ultrastructural examinations of the testis were performed in a patient with Down's syndrome. Plasma testosterone was abnormally low, and circulating levels of LH and FSH were higher than the normal range. The administration of HCG resulted in a low response of plasma testosterone. Electron microscopy revealed proliferation of smooth endoplasmic reticulum, an increase in paracrystalline inclusions and the absence of Reinke's crystals in Leydig cells.
对一名唐氏综合征患者的睾丸进行了激素和超微结构检查。血浆睾酮异常低，促黄体生成素（LH）和促卵泡生成素（FSH）的循环水平高于正常范围。注射人绒毛膜促性腺激素（HCG）后，血浆睾酮反应较低。电子显微镜检查显示，睾丸间质细胞中滑面内质网增生，副晶状包涵体增加，且无雷氏晶体。
