肾刷状缘小泡中胱氨酸与二碱基氨基酸的转运相互作用
Transport interaction of cystine and dibasic amino acids in renal brush border vesicles.
作者信息
Segal S, McNamara P D, Pepe L M
出版信息
Science. 1977 Jul 8;197(4299):169-71. doi: 10.1126/science.877548.
PMID:877548
Abstract
The uptake of cystine by vesicles prepared from rat kidney brush borders occurs by two distinct transport systems. The higher affinity system is inhibited by the dibasic amino acids lysine, arginine, and ornithine. The lower affinity system, unaffected by dibasic amino acids, appears to correspond to that observed by studying uptake of cystine by kidney slices.
摘要
从大鼠肾刷状缘制备的囊泡对胱氨酸的摄取通过两种不同的转运系统进行。高亲和力系统受到二碱基氨基酸赖氨酸、精氨酸和鸟氨酸的抑制。低亲和力系统不受二碱基氨基酸的影响，似乎与通过研究肾切片对胱氨酸的摄取所观察到的情况相符。
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