Hiraiwa H, Umemoto M, Take H
Department of Pediatrics, Kagoshima City Hospital, Japan.
Acta Paediatr Jpn. 1995 Dec;37(6):691-3. doi: 10.1111/j.1442-200x.1995.tb03405.x.
We investigated the prevalence of appendectomy in Japan to determine the tendency of familial aggregation on appendicitis using a large scale study. A total of 517 Japanese women (aged 20 to 45 years) served as the subjects and were questioned regarding their family history of appendectomy due to appendicitis. We compared the prevalence of appendectomy in children (subjects+their siblings) of three groups of families: (i) both parents affected; (ii) one parent affected; (iii) no parents affected. The differences between groups were statistically significant using contingency table and Chi-squared test. Our results suggest that about 40% of children with both parents affected, and about 20% of children with one parent affected may develop the disorder during childhood. This study may provide useful information in the nature of the development of appendicitis.
我们开展了一项大规模研究，调查日本阑尾切除术的患病率，以确定阑尾炎的家族聚集倾向。共有517名日本女性（年龄在20至45岁之间）作为研究对象，她们被问及因阑尾炎进行阑尾切除术的家族病史。我们比较了三组家庭中儿童（研究对象及其兄弟姐妹）阑尾切除术的患病率：（i）父母双方均患病；（ii）父母一方患病；（iii）父母均未患病。使用列联表和卡方检验，组间差异具有统计学意义。我们的结果表明，父母双方均患病的儿童中约40%，父母一方患病的儿童中约20%可能在童年时期患上该疾病。这项研究可能为阑尾炎的发病本质提供有用信息。
