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Perilla ketone: a potent lung toxin from the mint plant, Perilla frutescens Britton.

作者信息

Wilson B J, Garst J E, Linnabary R D, Channell R B

出版信息

Science. 1977 Aug 5;197(4303):573-4. doi: 10.1126/science.877573.

DOI:10.1126/science.877573
PMID:877573
Abstract

Perilla ketone, from the essential oil of Perilla frutescens, is a potent pulmonary edemagenic agent for laboratory animals and livestock. This finding would account for reported effects of the plant on grazing cattle. The use of perilla in oriental foods and medicinal preparations suggests possible hazards to human health as well.

摘要

相似文献

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Perilla ketone: a potent lung toxin from the mint plant, Perilla frutescens Britton.
Science. 1977 Aug 5;197(4303):573-4. doi: 10.1126/science.877573.
2
Intoxication of cattle by Perilla frutescens (purple mint).牛因紫苏(紫薄荷)中毒。
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Species susceptibility to the pulmonary toxicity of 3-furyl isoamyl ketone (perilla ketone): in vivo support for involvement of the lung monooxygenase system.物种对3-呋喃基异戊酮(紫苏酮)肺部毒性的易感性:体内实验支持肺单加氧酶系统参与其中。
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Perilla ketone: a model of increased pulmonary microvascular permeability pulmonary edema in sheep.紫苏酮:绵羊肺微血管通透性增加性肺水肿的一个模型。
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Effects of Perilla ketone on the in situ sheep lung.紫苏酮对原位羊肺的影响。
J Appl Physiol (1985). 1992 Feb;72(2):505-14. doi: 10.1152/jappl.1992.72.2.505.
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Toxicity of mould-damaged sweet potatoes (Ipomoea batatas).霉菌污染的红薯(甘薯)的毒性
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In vivo studies on the relationship between target organ alkylation and the pulmonary toxicity of a chemically reactive metabolite of 4-ipomeanol.关于靶器官烷基化与4-异戊烯醇化学反应性代谢物肺毒性之间关系的体内研究。
J Pharmacol Exp Ther. 1978 Dec;207(3):687-97.
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Acute bovine pulmonary emphysema produced by Perilla frutescens.紫苏引起的急性牛肺气肿。
Mod Vet Pract. 1978 Sep;59(9):684-6.
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GC-MS analysis of volatile compounds of Perilla frutescens Britton var. Japonica accessions: Morphological and seasonal variability.紫苏变种日本紫苏挥发性化合物的气相色谱-质谱分析:形态学和季节性变异性
Asian Pac J Trop Med. 2017 Jul;10(7):643-651. doi: 10.1016/j.apjtm.2017.07.004. Epub 2017 Jul 28.
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Development of tolerance to the pulmonary toxin, 4-ipomeanol.对肺部毒素4-异戊二烯醇的耐受性发展
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