Wang Ruo, Zhang Qianru, Feng Chengling, Zhang Juzhao, Qin Yuxuan, Meng Linghua
Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Evid Based Complement Alternat Med. 2022 Oct 28;2022:8809792. doi: 10.1155/2022/8809792. eCollection 2022.
As components of a traditional Chinese herbal medicine with many physiological activities, perilla ketone and isoegomaketone isolated from perilla essential oil are important active components of . Recent studies have shown that these two compounds have promising antitumor, antifungal, antirheumatoid arthritis, antiobesity, anti-inflammatory, healing-promoting, and other activities and can be used to combat toxicity from immunotherapy. Therefore, the multitude of pharmacological activities and effects demonstrate the broad research potential of perilla ketone and isoegomaketone. However, no reviews have been published related to the pharmacological activities or effects of perilla ketone and isoegomaketone. The purpose of this review is as follows: (1) outline the recent advances made in understanding the pharmacological activities of perilla ketone and isoegomaketone; (2) summarize their effects; and (3) discuss future research perspectives.
紫苏酮和异莪术酮是从紫苏精油中分离出来的具有多种生理活性的传统中草药成分，是其重要的活性成分。最近的研究表明，这两种化合物具有良好的抗肿瘤、抗真菌、抗类风湿性关节炎、抗肥胖、抗炎、促进愈合等活性，可用于对抗免疫疗法的毒性。因此，紫苏酮和异莪术酮的多种药理活性和作用显示出其广阔的研究潜力。然而，尚未发表有关紫苏酮和异莪术酮药理活性或作用的综述。本综述的目的如下：（1）概述紫苏酮和异莪术酮药理活性研究的最新进展；（2）总结它们的作用；（3）讨论未来的研究前景。
