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先兆流产对妊娠结局的影响。

The effects of threatened abortions on pregnancy outcomes.

作者信息

Kanmaz Ahkam Göksel, İnan Abdurrahman Hamdi, Beyan Emrah, Budak Adnan

机构信息

Izmir Tepecik Teaching and Research Hospital, Department of Obstetrics and Gynecology, Izmir, Turkey.

Izmir Provincial Health Directorate, Izmir, Turkey.

出版信息

Ginekol Pol. 2019;90(4):195-200. doi: 10.5603/GP.a2019.0035. Epub 2019 Mar 22.

DOI:10.5603/GP.a2019.0035
PMID:30901073
Abstract

OBJECTIVES

The effects of first trimester threatened abortions on prenatal and postnatal pregnancy outcomes.

MATERIAL AND METHODS

Data from 24.835 pregnant women were retrospectively analysed. The pregnant women were divided into two groups according to whether they had a first trimester threatened abortion or not. The demographic data and prenatal, postnatal and labour outcomes were compared for the two groups. Those cases with miscarriages during their follow-up, pregnant women with systemic diseases, multiple pregnancies and patients who were diagnosed with cervical erosion and cervical polypoid formation during vaginal bleeding examinations were all excluded.

RESULTS

The age (p < 0.001), ART pregnancy rate (p = 0.03) and nulliparity rate (p = 0.013) in those with the risk of miscar- riage were statistically significantly higher than those without the risk. The gestational weeks (p < 0.001) and birth weights (p < 0.001) were significantly lower for the miscarriage group than in the control group. Hyperemesis gravidarum (p < 0.001), gestational diabetes mellitus (GDM) (p < 0.001) and placenta previa (p = 0.018) rates were statistically significantly and more frequent in the pregnancies with the threatened abortion group than in the control group. The rates of caesarean delivery were statistically significantly higher in the threatened abortion group (p < 0.001).

CONCLUSIONS

Threatened abortion between 6- and 14-weeks gestational age is a complication that may cause anxiety in the early weeks of pregnancy. But the treatment, follow-up and cause of threatened abortion all remain unclear.

摘要

目的

探讨孕早期先兆流产对产前及产后妊娠结局的影响。

材料与方法

回顾性分析24835例孕妇的数据。根据孕妇孕早期是否有先兆流产将其分为两组。比较两组的人口统计学数据以及产前、产后和分娩结局。排除随访期间流产的病例、患有全身性疾病的孕妇、多胎妊娠以及在阴道出血检查中被诊断为宫颈糜烂和宫颈息肉样形成的患者。

结果

有流产风险的孕妇在年龄(p<0.001)、辅助生殖技术妊娠率(p = 0.03)和未生育率(p = 0.013)方面显著高于无流产风险的孕妇。流产组的孕周(p<0.001)和出生体重(p<0.001)显著低于对照组。妊娠剧吐(p<0.001)、妊娠期糖尿病(GDM)(p<0.001)和前置胎盘(p = 0.018)的发生率在先兆流产组妊娠中显著高于对照组,且更常见。先兆流产组剖宫产率显著更高(p<0.001)。

结论

孕龄6至14周的先兆流产是一种可能在妊娠早期引起焦虑的并发症。但先兆流产的治疗、随访及病因仍不明确。

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