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超声及双功多普勒在门静脉高压症诊断及随访中的应用

Ultrasound and duplex-Doppler in the diagnosis and follow-up of portal hypertension.

作者信息

Michielsen P P, Duysburgh I K, Pelckmans P A

机构信息

Division of Gastroenterology, University of Antwerp.

出版信息

Acta Gastroenterol Belg. 1995 Sep-Dec;58(5-6):409-21.

PMID:8775998
Abstract

Ultrasound examination should be carried out as the first investigation in all patients with suspected hepatobiliary disease. It has a high accuracy in detecting signs of portal hypertension such as ascites, splenomegaly and collateral veins. The most common cause of portal hypertension in the Western world is cirrhosis. Although there is an overlap of ultrasound findings in normal liver, fatty liver, chronic liver disease with and without fibrosis, and cirrhosis, a correct diagnosis of cirrhosis by judgment of ultrasound findings is reported to be achieved in up to 80%. Diagnostic parameters used are size and outline of the liver, its reflectivity and attenuation of the echo-pattern. If used in combination with the Doppler duplex system, the information gained vastly increases. Areas where this technique is able to provide useful and reliable data have been defined in a consensus conference held in Bologna. Doppler flowmetry of hepatic vessels allows detection of presence, direction and characteristics of blood flow. The reliability of the quantitative measurements of blood flow in abdominal vessels is still questioned. When using the same equipment by skilled operators, however, duplex-Doppler data of the portal vein are of value in the assessment of the risk of variceal bleeding, in the evaluation of the progression of liver disease and in the evaluation of medical therapy for portal hypertension. Furthermore, the technique is of practical value in pre-and postoperative examinations for shunt surgery as well as in the pre-procedural work-up of transjugular intrahepatic portosystemic stent shunt (TIPS), during the TIPS procedure and in the post-TIPS followup.

摘要

对于所有疑似肝胆疾病的患者,超声检查应作为首要检查手段。它在检测门静脉高压的征象如腹水、脾肿大和侧支静脉方面具有较高的准确性。在西方世界,门静脉高压最常见的病因是肝硬化。尽管正常肝脏、脂肪肝、有无纤维化的慢性肝病以及肝硬化的超声表现存在重叠,但据报道,通过超声表现判断肝硬化的正确诊断率可达80%。所使用的诊断参数包括肝脏的大小和轮廓、其回声模式的反射率和衰减。如果与多普勒双功系统联合使用,获得的信息将大大增加。在博洛尼亚举行的一次共识会议上,已经确定了这项技术能够提供有用和可靠数据的领域。肝血管的多普勒血流测量可以检测血流的存在、方向和特征。腹部血管血流定量测量的可靠性仍受到质疑。然而,当由熟练的操作人员使用相同设备时,门静脉的双功多普勒数据在评估静脉曲张出血风险、评估肝病进展以及评估门静脉高压的药物治疗方面具有价值。此外,该技术在分流手术的术前和术后检查以及经颈静脉肝内门体分流术(TIPS)的术前准备、TIPS手术期间和TIPS术后随访中具有实际应用价值。

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