Wang C K, Lee J Y
Department of Dermatology, National Cheng Kung University Medical Center, Tainan, Taiwan, Republic of China.
Br J Dermatol. 1996 Jul;135(1):135-8.
We report two patients with an unusual variant of macular amyloidosis who had diffuse homogeneous hyperpigmentation without papules, a rippled pattern or poikiloderma. The hyperpigmentation was extensive, involving the face, neck, mucosa, axillae, groin and peripheries in one patient and only the face and arms in the other. Skin biopsies in both cases revealed subepidermal band-like amyloid deposits. Neither patient had systemic involvement. The skin lesions in these patients could be easily confused with hyperpigmentation caused by endocrine disorders, drugs, heavy metals, polychlorinated biphenyl or cutaneous inflammation.
我们报告了两名患有黄斑淀粉样变性异常变体的患者，他们有弥漫性均匀色素沉着，无丘疹、波纹状图案或皮肤异色症。色素沉着广泛，一例累及面部、颈部、黏膜、腋窝、腹股沟和四肢，另一例仅累及面部和手臂。两例皮肤活检均显示表皮下带状淀粉样蛋白沉积。两名患者均无全身受累。这些患者的皮肤病变很容易与内分泌紊乱、药物、重金属、多氯联苯或皮肤炎症引起的色素沉着相混淆。
