Age-related changes in the color-match-area effect.

Color matches were measured as a function of field diameter (1, 2, 4 and 8 deg) for 53 normal observers aged 13-80 yr. The difference between match midpoints for the 1 deg diameter and the other diameters decreased throughout adulthood, indicating an age-related change in optical density of cone outer segments in the central 1 deg. For all ages, there were large interobserver differences in the magnitude of the difference scores. These results provide an explanation for contradictions in the literature on the effects of age on cone optical density and on the magnitude of the color-match-area effect.