Okano M, Nishioka K, Nagano T, Ohta N, Masuda Y
Department of Otorhinolarygology, Tottori Municipal Hospital.
Arerugi. 1994 Sep;43(9):1179-84.
Clinical characterization of patients with allergy to Chamaecyparis obtusa (Cypress) pollen and their specific IgE antibody was investigated by using AlaSTAT assay, a new method for measurement of antigen-specific IgE antibody. Positive rate of antigen-specific antibody in patients with allergic pollinosis was 83.5% for Japanese cedar pollen and 80.0% for Chamaecyparis obtusa pollen. 76.4% of patients were sensitized both to Japanese cedar and Chamaecyparis obtusa pollen, however, 7.9% were sensitized only to the latter. As for clinical symptoms, duration of attack was short and severity was mild or moderate in the patients sensitized only to Chamaecyparis obtusa pollen. Patients who visited hospital in April, in that Chamaecyparis obtusa pollen disseminated in the air predominantly, showed significant elevation in AlaSTAT scores compared with patients who visited in February and March (p < 0.05).
采用AlaSTAT检测法（一种测量抗原特异性IgE抗体的新方法），对扁柏花粉过敏患者及其特异性IgE抗体进行了临床特征研究。变应性花粉症患者中，日本柳杉花粉抗原特异性抗体阳性率为83.5%，扁柏花粉为80.0%。76.4%的患者对日本柳杉和扁柏花粉均致敏，然而，7.9%的患者仅对后者致敏。至于临床症状，仅对扁柏花粉致敏的患者发作持续时间短，严重程度为轻度或中度。4月就诊的患者，此时空气中主要传播扁柏花粉，与2月和3月就诊的患者相比，AlaSTAT评分显著升高（p<0.05）。
