Eastell R
Department of Human Metabolism and Clinical Biochemistry, University of Sheffield, UK.
Bone. 1996 Mar;18(3 Suppl):203S-207S. doi: 10.1016/8756-3282(95)00503-x.
Bone mineral density of the distal forearm decreases with age in women, and this results in an increased risk of forearm fractures. Men have no increase in risk of forearm fractures with age because they have a higher peak bone mass at this site and less of a decrease in bone mineral density with ageing. Bone loss from the forearm slows in women after the age of 65 years in women and this may account for the plateau in forearm fracture rate after this age. Women with forearm fractures have twice the expected risk of vertebral and hip fractures. Forearm fractures before the age of 60 years are associated with an increase in the risk of vertebral fractures. Forearm fractures after the age of 70 years are associated with an increased risk of hip fractures. Thus, women presenting with forearm fractures are a good target population for the prevention of osteoporosis.
女性前臂远端的骨矿物质密度随年龄增长而降低，这导致前臂骨折风险增加。男性前臂骨折风险不会随年龄增长而增加，因为他们在该部位的骨峰值较高，且随着年龄增长骨矿物质密度下降较少。65岁以后女性前臂的骨质流失减缓，这可能是该年龄后前臂骨折率趋于平稳的原因。发生前臂骨折的女性发生椎体和髋部骨折的风险是预期风险的两倍。60岁之前发生的前臂骨折与椎体骨折风险增加有关。70岁之后发生的前臂骨折与髋部骨折风险增加有关。因此，出现前臂骨折的女性是预防骨质疏松症的良好目标人群。
