Bruck D, Parkes J D
Department of Psychology, Victoria University, Melbourne, Australia.
J Neurol Neurosurg Psychiatry. 1996 May;60(5):576-8. doi: 10.1136/jnnp.60.5.576.
Eighteen patients with idiopathic hypersomnia (IH) were compared with 50 patients with the narcoleptic syndrome of cataplexy and daytime sleepiness (NLS) using self report questionnaires and a diary of sleep/wake patterns. The IH group reported more consolidated nocturnal sleep, a lower propensity to nap, greater refreshment after naps, and a greater improvement in excessive daytime sleepiness since onset than the NLS group. In IH, the onset of excessive daytime sleepiness was predominantly associated with familial inheritance or a viral illness. Two variable--number of reported awakenings during nocturnal sleep and the reported change in sleepiness since onset--provided maximum discrimination between the IH and NLS groups. Confusional arousals, extended naps or nocturnal sleep, autonomic nervous system dysfunction, low ratings of medication effectiveness, or side effects of medication were not associated differentially with either IH or NLS.
使用自我报告问卷和睡眠/觉醒模式日记,对18名特发性嗜睡症(IH)患者与50名有猝倒和日间嗜睡发作性睡病综合征(NLS)患者进行了比较。与NLS组相比,IH组报告夜间睡眠更巩固,小睡倾向更低,小睡后更精神,且自发病以来日间过度嗜睡情况改善更大。在IH中,日间过度嗜睡的发作主要与家族遗传或病毒感染有关。两个变量——夜间睡眠中报告的觉醒次数和自发病以来报告的嗜睡变化——在IH组和NLS组之间提供了最大的区分度。意识模糊觉醒、延长小睡或夜间睡眠、自主神经系统功能障碍、药物疗效评分低或药物副作用在IH或NLS中均无差异关联。