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白花蒿对正常及四氧嘧啶诱导的糖尿病大鼠血糖水平的影响。

Effects of Artemisia pallens Wall. on blood glucose levels in normal and alloxan-induced diabetic rats.

作者信息

Subramoniam A, Pushpangadan P, Rajasekharan S, Evans D A, Latha P G, Valsaraj R

机构信息

Division of Ethnopharmacology, Tropical Botanic Garden and Research Institute, Palode, Kerala, India.

出版信息

J Ethnopharmacol. 1996 Jan;50(1):13-7. doi: 10.1016/0378-8741(95)01329-6.

DOI:10.1016/0378-8741(95)01329-6
PMID:8778502
Abstract

Oral administration of the methanol extract of the aerial parts of Artemisia pallens Wall. (used in Indian folk medicine for the treatment of diabetes mellitus) led to significant blood glucose lowering effect in glucose-fed hyperglycaemic and alloxan-induced diabetic rats. This effect of the extract was dose dependent and significant at 100 mg/kg level in glucose-fed rats. In fasted normal rats, the extract caused a moderate hypoglycaemic effect at a higher dose (1000 mg/kg). The water extract (1000 mg/kg) was inactive.

摘要

口服白花蒿(Artemisia pallens Wall.)地上部分的甲醇提取物(印度民间医学中用于治疗糖尿病),可使葡萄糖喂养的高血糖大鼠和四氧嘧啶诱导的糖尿病大鼠的血糖显著降低。提取物的这种作用呈剂量依赖性,在葡萄糖喂养的大鼠中,100mg/kg剂量时效果显著。在禁食的正常大鼠中,提取物在较高剂量(1000mg/kg)时引起中度低血糖作用。水提取物(1000mg/kg)无活性。

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