Driver P J, Lemp M A
Eye Institute at Cooper Hospital/University Medical Center, Camden, New Jersey, USA.
Surv Ophthalmol. 1996 Mar-Apr;40(5):343-67. doi: 10.1016/s0039-6257(96)80064-6.
Blepharitis is probably the most common disease entity seen in the general ophthalmologist's office. A significant proportion of these cases are secondary to meibomian gland disease. This review outlines our knowledge of the histopathology, lipid abnormalities and role of microorganisms in meibomian gland dysfunction. We will also review the physiology of meibomian gland secretion and present models of meibomian gland dysfunction which have enhanced our knowledge of this condition. The importance of diagnosing associated conditions such as aqueous tear deficiency, contact lens intolerance, rosacea, and seborrheic dermatitis is emphasized. Although this condition causes significant morbidity in the population, there are effective treatments available and these will be discussed.
睑缘炎可能是普通眼科医生办公室中最常见的疾病实体。这些病例中有很大一部分继发于睑板腺疾病。本综述概述了我们对睑板腺功能障碍的组织病理学、脂质异常和微生物作用的认识。我们还将回顾睑板腺分泌的生理学，并介绍增强我们对这种情况认识的睑板腺功能障碍模型。强调了诊断相关病症如泪液分泌不足、隐形眼镜不耐受、酒渣鼻和脂溢性皮炎的重要性。尽管这种情况在人群中会导致显著的发病率，但有有效的治疗方法，将对此进行讨论。
