Siderowf A D, Balcer L J, Kenyon L C, Nei M, Raps E C, Galetta S L
Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia 19104, USA.
Neurology. 1996 Apr;46(4):1160-2. doi: 10.1212/wnl.46.4.1160.
A 57-year-old awake man developed central neurogenic hyperventilation associated with a pontine mass. Serum pH reached as high as 7.72 with serum carbon dioxide of 6 torr. Examination of CSF during overbreathing showed that CSF pH was markedly alkaline. Pathologic study showed a well-differentiated pontine astrocytoma. The combination of alkaline CSF and an infiltrating pontine lesion supports a structural, rather than chemical, mechanism for central hyperventilation.
一名57岁清醒男性出现与脑桥肿物相关的中枢性神经源性过度通气。血清pH值高达7.72，血清二氧化碳分压为6托。过度呼吸期间脑脊液检查显示脑脊液pH值明显呈碱性。病理研究显示为高分化脑桥星形细胞瘤。脑脊液碱性与浸润性脑桥病变相结合支持中枢性过度通气的结构而非化学机制。
